PARP1-catalyzed PARylation of YY1 mediates endoplasmic reticulum stress in granulosa cells to determine primordial follicle activation

PARP1-catalyzed PARylation of YY1 mediates endoplasmic reticulum stress in granulosa cells to determine primordial follicle activation

Abstract Although only a small number of primordial follicles are known to be selectively activated during female reproductive cycles, the mechanisms that trigger this recruitment remain largely uncharacterized. Misregulated activation of primordial follicles may lead to the exhaustion of the non-re...

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Bibliographic Details
Main Authors: Wei Chen, Qiukai E, Bo Sun, Pengxue Zhang, Nan Li, Shujia Fei, Yingnan Wang, Shuting Liu, Xiaoqiu Liu, Xuesen Zhang
Format: Article
Language:English
Published: Nature Publishing Group 2023-08-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-023-05984-w

Internet

https://doi.org/10.1038/s41419-023-05984-w

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