Systems biology and machine learning approaches identify drug targets in diabetic nephropathy

Abstract Diabetic nephropathy (DN), the leading cause of end-stage renal disease, has become a massive global health burden. Despite considerable efforts, the underlying mechanisms have not yet been comprehensively understood. In this study, a systematic approach was utilized to identify the microRN...

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Bibliographic Details
Main Authors: Maryam Abedi, Hamid Reza Marateb, Mohammad Reza Mohebian, Seyed Hamid Aghaee-Bakhtiari, Seyed Mahdi Nassiri, Yousof Gheisari
Format: Article
Language:English
Published: Nature Portfolio 2021-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-02282-3