Sex-specific DNA methylation differences in Alzheimer’s disease pathology

Sex-specific DNA methylation differences in Alzheimer’s disease pathology

Abstract Sex is an important factor that contributes to the clinical and biological heterogeneities in Alzheimer’s disease (AD), but the regulatory mechanisms underlying sex disparity in AD are still not well understood. DNA methylation is an important epigenetic modification that regulates gene tra...

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Bibliographic Details
Main Authors: Lanyu Zhang, Juan I. Young, Lissette Gomez, Tiago C. Silva, Michael A. Schmidt, Jesse Cai, Xi Chen, Eden R. Martin, Lily Wang
Format: Article
Language:English
Published: BMC 2021-04-01
Series:Acta Neuropathologica Communications
Subjects:
Alzheimer’s disease
Sex-specific
DNA methylation
Epigenome-wide association study
Online Access:https://doi.org/10.1186/s40478-021-01177-8

Internet

https://doi.org/10.1186/s40478-021-01177-8

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