Dose-Dependent Effects in Plasma Oncotherapy: Critical In Vivo Immune Responses Missed by In Vitro Studies

Dose-Dependent Effects in Plasma Oncotherapy: Critical In Vivo Immune Responses Missed by In Vitro Studies

Cold atmospheric plasma (CAP) generates abundant reactive oxygen and nitrogen species (ROS and RNS, respectively) which can induce apoptosis, necrosis, and other biological responses in tumor cells. However, the frequently observed different biological responses to in vitro and in vivo CAP treatment...

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Bibliographic Details
Main Authors: Yuanyuan He, Fanwu Gong, Tao Jin, Qi Liu, Haopeng Fang, Yan Chen, Guomin Wang, Paul K. Chu, Zhengwei Wu, Kostya (Ken) Ostrikov
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Biomolecules
Subjects:
cold atmospheric plasma
in vitro and in vivo plasma treatments
dose-dependent effects
tumor microenvironment
ROS/RNS
Online Access:https://www.mdpi.com/2218-273X/13/4/707

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https://www.mdpi.com/2218-273X/13/4/707

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