Bisphenol S decreased lifespan and healthspan via insulin/IGF-1-like signaling-against mitochondrial stress in Caenorhabditis elegans

Bisphenol S (BPS) is widely presented and affects aging with unclear mechanisms. Here, we applied C. elegans to evaluate the effects of BPS on lifespan and healthspan and to investigate the underlying mechanisms. Both early-life and whole-life exposure to BPS at environmentally relevant doses (0.6,...

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Main Authors: Wenmiao He, Zhiwei Liu, Hongchao Zhang, Qian Liu, Zhenkun Weng, Dongmei Wang, Wenhui Guo, Jin Xu, Dayong Wang, Zhaoyan Jiang, Aihua Gu
Format: Article
Jezik:English
Izdano: Elsevier 2024-10-01
Serija:Ecotoxicology and Environmental Safety
Teme:
Online dostop:http://www.sciencedirect.com/science/article/pii/S0147651324012120