Transduction Enhancers Enable Efficient Human Adenovirus Type 5-Mediated Gene Transfer into Human Multipotent Mesenchymal Stromal Cells

Transduction Enhancers Enable Efficient Human Adenovirus Type 5-Mediated Gene Transfer into Human Multipotent Mesenchymal Stromal Cells

Human multipotent mesenchymal stromal cells (hMSCs) are currently developed as cell therapeutics for different applications, including regenerative medicine, immune modulation, and cancer treatment. The biological properties of hMSCs can be further modulated by genetic engineering. Viral vectors bas...

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Bibliographic Details
Main Authors: Robin Nilson, Olivia Lübbers, Linus Weiß, Karmveer Singh, Karin Scharffetter-Kochanek, Markus Rojewski, Hubert Schrezenmeier, Philip Helge Zeplin, Wolfgang Funk, Lea Krutzke, Stefan Kochanek, Astrid Kritzinger
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Viruses
Subjects:
hMSC
mesenchymal stromal cells
mesenchymal stem cells
adenovirus
gene therapy
transduction enhancer
Online Access:https://www.mdpi.com/1999-4915/13/6/1136

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https://www.mdpi.com/1999-4915/13/6/1136

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