Antimicrobial mitochondrial reactive oxygen species induction by lung epithelial immunometabolic modulation.

Antimicrobial mitochondrial reactive oxygen species induction by lung epithelial immunometabolic modulation.

Pneumonia is a worldwide threat, making discovery of novel means to combat lower respiratory tract infection an urgent need. Manipulating the lungs' intrinsic host defenses by therapeutic delivery of certain pathogen-associated molecular patterns protects mice against pneumonia in a reactive ox...

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Bibliographic Details
Main Authors: Yongxing Wang, Vikram V Kulkarni, Jezreel Pantaleón García, Miguel M Leiva-Juárez, David L Goldblatt, Fahad Gulraiz, Lisandra Vila Ellis, Jichao Chen, Michael K Longmire, Sri Ramya Donepudi, Philip L Lorenzi, Hao Wang, Lee-Jun Wong, Michael J Tuvim, Scott E Evans
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-09-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1011138

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https://doi.org/10.1371/journal.ppat.1011138

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