A glutamate receptor C-tail recruits CaMKII to suppress retrograde homeostatic signaling

A glutamate receptor C-tail recruits CaMKII to suppress retrograde homeostatic signaling

Presynaptic homeostatic plasticity adaptively enhances neurotransmitter release following diminished postsynaptic glutamate receptor functionality. Here the authors identify a calcium-independent signaling system where active CaMKII detects a short domain encoded in a glutamate receptor C-tail, whic...

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Bibliographic Details
Main Authors: Sarah Perry, Yifu Han, Chengjie Qiu, Chun Chien, Pragya Goel, Samantha Nishimura, Manisha Sajnani, Andreas Schmid, Stephan J. Sigrist, Dion Dickman
Format: Article
Language:English
Published: Nature Portfolio 2022-12-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-35417-9

Internet

https://doi.org/10.1038/s41467-022-35417-9

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