Immune Checkpoints, a Novel Class of Therapeutic Targets for Autoimmune Diseases

Autoimmune diseases, such as multiple sclerosis and type-1 diabetes, are the outcomes of a failure of immune tolerance. Immune tolerance is sustained through interplays between two inter-dependent clusters of immune activities: immune stimulation and immune regulation. The mechanisms of immune regul...

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Bibliographic Details
Main Authors: Yujia Zhai, Reza Moosavi, Mingnan Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.645699/full