Iron dyshomeostasis and time-course changes in iron-uptake systems and ferritin level in relation to pro-inflammatory microglia polarization in sepsis-induced encephalopathy

Encephalopathy is a frequent and lethal consequence of sepsis. Recently, a growing body of evidence has provided important insights into the role of iron dyshomeostasis in the context of inflammation. The molecular mechanisms underlying iron dyshomeostasis and its relationship with macrophage phenot...

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Bibliographic Details
Main Authors: Nivin Sharawy, Ahmad Abdel-Aliem Imam, Basma Emad Aboulhoda, Mohamed Mansour Khalifa, George N. B. Morcos, Waleed Ahmed Abd Algaleel, Passant E. Moustafa, Marwan A. Abdelbaset, Tarek Shoukry
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Physiology
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Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2022.953206/full