A camel-derived MERS-CoV with a variant spike protein cleavage site and distinct fusion activation properties

A camel-derived MERS-CoV with a variant spike protein cleavage site and distinct fusion activation properties

Middle East respiratory syndrome coronavirus (MERS-CoV) continues to circulate in both humans and camels, and the origin and evolution of the virus remain unclear. Here we characterize the spike protein of a camel-derived MERS-CoV (NRCE-HKU205) identified in 2013, early in the MERS outbreak. NRCE-HK...

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Bibliographic Details
Main Authors: Jean Kaoru Millet, Monty E Goldstein, Rachael N Labitt, Hung-Lun Hsu, Susan Daniel, Gary R Whittaker
Format: Article
Language:English
Published: Taylor & Francis Group 2016-01-01
Series:Emerging Microbes and Infections
Subjects:
camel
coronavirus
furin
fusion activation
MERS
spike
Online Access:https://www.tandfonline.com/doi/10.1038/emi.2016.125

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https://www.tandfonline.com/doi/10.1038/emi.2016.125

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