Flick the cancer stem cells' switch to turn cancer off

Tumors are organized in a cellular hierarchy with a population of cancer stem cell (CSC) driving cancer progression and resistance to treatment. Recently, we identified miR-600 as a bimodal switcher that balances breast CSC-fate from a self-renewing to a differentiation state, with a direct impact o...

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Bibliographic Details
Main Authors: Christophe Ginestier, Daniel Birnbaum, Emmanuelle Charafe-Jauffret
Format: Article
Language:English
Published: Taylor & Francis Group 2017-07-01
Series:Molecular & Cellular Oncology
Subjects:
Online Access:http://dx.doi.org/10.1080/23723556.2017.1319896