Flick the cancer stem cells' switch to turn cancer off
Tumors are organized in a cellular hierarchy with a population of cancer stem cell (CSC) driving cancer progression and resistance to treatment. Recently, we identified miR-600 as a bimodal switcher that balances breast CSC-fate from a self-renewing to a differentiation state, with a direct impact o...
| المؤلفون الرئيسيون: | , , |
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| التنسيق: | مقال |
| اللغة: | English |
| منشور في: |
Taylor & Francis Group
2017-07-01
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| سلاسل: | Molecular & Cellular Oncology |
| الموضوعات: | |
| الوصول للمادة أونلاين: | http://dx.doi.org/10.1080/23723556.2017.1319896 |
| الملخص: | Tumors are organized in a cellular hierarchy with a population of cancer stem cell (CSC) driving cancer progression and resistance to treatment. Recently, we identified miR-600 as a bimodal switcher that balances breast CSC-fate from a self-renewing to a differentiation state, with a direct impact on tumor progression. |
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| تدمد: | 2372-3556 |