Flick the cancer stem cells' switch to turn cancer off
Tumors are organized in a cellular hierarchy with a population of cancer stem cell (CSC) driving cancer progression and resistance to treatment. Recently, we identified miR-600 as a bimodal switcher that balances breast CSC-fate from a self-renewing to a differentiation state, with a direct impact o...
| Hauptverfasser: | , , |
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| Format: | Artikel |
| Sprache: | English |
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Taylor & Francis Group
2017-07-01
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| Schriftenreihe: | Molecular & Cellular Oncology |
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| Online Zugang: | http://dx.doi.org/10.1080/23723556.2017.1319896 |
| Zusammenfassung: | Tumors are organized in a cellular hierarchy with a population of cancer stem cell (CSC) driving cancer progression and resistance to treatment. Recently, we identified miR-600 as a bimodal switcher that balances breast CSC-fate from a self-renewing to a differentiation state, with a direct impact on tumor progression. |
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| ISSN: | 2372-3556 |