Flick the cancer stem cells' switch to turn cancer off
Tumors are organized in a cellular hierarchy with a population of cancer stem cell (CSC) driving cancer progression and resistance to treatment. Recently, we identified miR-600 as a bimodal switcher that balances breast CSC-fate from a self-renewing to a differentiation state, with a direct impact o...
| Главные авторы: | , , |
|---|---|
| Формат: | Статья |
| Язык: | English |
| Опубликовано: |
Taylor & Francis Group
2017-07-01
|
| Серии: | Molecular & Cellular Oncology |
| Предметы: | |
| Online-ссылка: | http://dx.doi.org/10.1080/23723556.2017.1319896 |
| Итог: | Tumors are organized in a cellular hierarchy with a population of cancer stem cell (CSC) driving cancer progression and resistance to treatment. Recently, we identified miR-600 as a bimodal switcher that balances breast CSC-fate from a self-renewing to a differentiation state, with a direct impact on tumor progression. |
|---|---|
| ISSN: | 2372-3556 |