Flick the cancer stem cells' switch to turn cancer off
Tumors are organized in a cellular hierarchy with a population of cancer stem cell (CSC) driving cancer progression and resistance to treatment. Recently, we identified miR-600 as a bimodal switcher that balances breast CSC-fate from a self-renewing to a differentiation state, with a direct impact o...
| Asıl Yazarlar: | , , |
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| Materyal Türü: | Makale |
| Dil: | English |
| Baskı/Yayın Bilgisi: |
Taylor & Francis Group
2017-07-01
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| Seri Bilgileri: | Molecular & Cellular Oncology |
| Konular: | |
| Online Erişim: | http://dx.doi.org/10.1080/23723556.2017.1319896 |
| Özet: | Tumors are organized in a cellular hierarchy with a population of cancer stem cell (CSC) driving cancer progression and resistance to treatment. Recently, we identified miR-600 as a bimodal switcher that balances breast CSC-fate from a self-renewing to a differentiation state, with a direct impact on tumor progression. |
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| ISSN: | 2372-3556 |