Enhanced attenuation of chikungunya vaccines expressing antiviral cytokines
Abstract Alphaviruses are vector-borne, medically relevant, positive-stranded RNA viruses that cause disease in animals and humans worldwide. Of this group, chikungunya virus (CHIKV) is the most significant human pathogen, responsible for generating millions of infections leading to severe febrile i...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2024-03-01
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Series: | npj Vaccines |
Online Access: | https://doi.org/10.1038/s41541-024-00843-x |