Genetic Features of HIV-1 Integrase Sub-Subtype A6 Predominant in Russia and Predicted Susceptibility to INSTIs

Genetic Features of HIV-1 Integrase Sub-Subtype A6 Predominant in Russia and Predicted Susceptibility to INSTIs

The increasing use of the integrase strand transfer inhibitor (INSTI) class for the treatment of HIV-infection has pointed to the importance of analyzing the features of HIV-1 subtypes for an improved understanding of viral genetic variability in the occurrence of drug resistance (DR). In this study...

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Bibliographic Details
Main Authors: Alina Kirichenko, Ilya Lapovok, Pavel Baryshev, David A. M. C. van de Vijver, Jeroen J. A. van Kampen, Charles A. B. Boucher, Dimitrios Paraskevis, Dmitry Kireev
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Viruses
Subjects:
HIV-1
A6
integrase
INSTI
L74I
polymorphisms
Online Access:https://www.mdpi.com/1999-4915/12/8/838

Internet

https://www.mdpi.com/1999-4915/12/8/838

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