Pharmacological modulation of TSPO in microglia/macrophages and neurons in a chronic neurodegenerative model of prion disease

Pharmacological modulation of TSPO in microglia/macrophages and neurons in a chronic neurodegenerative model of prion disease

Abstract Neuroinflammation is an important component of many neurodegenerative diseases, whether as a primary cause or a secondary outcome. For that reason, either as diagnostic tools or to monitor progression and/or pharmacological interventions, there is a need for robust biomarkers of neuroinflam...

Full description

Bibliographic Details
Main Authors: Marta Vicente-Rodríguez, Renzo Mancuso, Alba Peris-Yague, Camilla Simmons, NIMA Consortium, Diego Gómez-Nicola, V. Hugh Perry, Federico Turkheimer, Simon Lovestone, Christine A. Parker, Diana Cash
Format: Article
Language:English
Published: BMC 2023-04-01
Series:Journal of Neuroinflammation
Subjects:
Astrocytes
CSF1R
ME7
Microglia
Neuroinflammation
Neurons
Online Access:https://doi.org/10.1186/s12974-023-02769-y

Internet

https://doi.org/10.1186/s12974-023-02769-y

Similar Items