ZNF24 regulates the progression of KRAS mutant lung adenocarcinoma by promoting SLC7A5 translation

ZNF24 regulates the progression of KRAS mutant lung adenocarcinoma by promoting SLC7A5 translation

BackgroundClinical treatment of RAS mutant cancers is challenging because of the complexity of the Ras signaling pathway. SLC7A5 is a newly discovered downstream gene of the Ras signaling pathway, but the regulatory mechanism is unclear. We aimed to explore the molecular mechanism and role in KRAS m...

Full description

Bibliographic Details
Main Authors: Daqi Jia, Leilei Li, Peng Wang, Qiang Feng, Xinyan Pan, Peng Lin, Shuling Song, Lilin Yang, Julun Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Oncology
Subjects:
KRAS mutation
lung adenocarcinoma
SLC7A5
ZNF24
protein interaction
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.1043177/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2022.1043177/full

Similar Items