Dehydrocostus lactone ameliorates lipid accumulation, insulin resistance, and endoplasmic reticulum stress in palmitate-treated hepatocytes

Abstract Fatty liver disease is caused by lipid accumulation in the liver, insulin resistance (IR), reactive oxygen species (ROS), and endoplasmic reticulum (ER) stress. Dehydrocostus lactone (DHE) has anticancer, anti-inflammatory, and anti-ulcer effects. However, its effects on hepatic steatosis a...

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Bibliographic Details
Main Authors: Yeonhee Hong, Minji Lee, Chanseul Kim, Gun-Hwa Kim
Format: Article
Language:English
Published: SpringerOpen 2022-10-01
Series:Journal of Analytical Science and Technology
Subjects:
Online Access:https://doi.org/10.1186/s40543-022-00349-y