High expression of WNT7A predicts poor prognosis and promote tumor metastasis in pancreatic ductal adenocarcinoma

High expression of WNT7A predicts poor prognosis and promote tumor metastasis in pancreatic ductal adenocarcinoma

Abstract Due to the therapy resistance and frequent metastasis, pancreatic ductal adenocarcinoma(PDAC) remains one of the most malignant carcinoma. WNT7A, an important ligand of Wnt/β-catenin signaling pathways, has a controversial role in tumor development. The role of WNT7A in PDAC remains unclear...

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Bibliographic Details
Main Authors: Dong-jin Wu, Yong-sheng Jiang, Rui-zhe He, Ling-ye Tao, Min-wei Yang, Xue-liang Fu, Jiang-yu Yang, Kun Zhu
Format: Article
Language:English
Published: Nature Portfolio 2018-10-01
Series:Scientific Reports
Subjects:
Pancreatic Ductal Adenocarcinoma (PDAC)
Wnt5a Expression
Performed Transwell Assays
PDAC Tissue
PDAC Patients
Online Access:https://doi.org/10.1038/s41598-018-34094-3

Internet

https://doi.org/10.1038/s41598-018-34094-3

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