Determination of Antidepressants and Antipsychotics in Dried Blood Spots (DBSs) Collected from Post-Mortem Samples and Evaluation of the Stability over a Three-Month Period

Determination of Antidepressants and Antipsychotics in Dried Blood Spots (DBSs) Collected from Post-Mortem Samples and Evaluation of the Stability over a Three-Month Period

An LC-MS/MS method for the identification and quantification of antidepressants and antipsychotics was developed on dried blood spots (DBSs). Moreover, analyte stability on DBSs within a 3-month period was monitored. Aliquots of 85 µL of blood from autopsy cases were pipetted onto DBS cards...

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Bibliographic Details
Main Authors: Matteo Moretti, Francesca Freni, Beatrice Valentini, Claudia Vignali, Angelo Groppi, Silvia Damiana Visonà, Antonio Marco Maria Osculati, Luca Morini
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:Molecules
Subjects:
dried blood spot
antidepressants
antipsychotics
lc-ms/ms
post-mortem
stability
Online Access:https://www.mdpi.com/1420-3049/24/20/3636

Internet

https://www.mdpi.com/1420-3049/24/20/3636

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