Novel versatile synthesis method for amides, carbamates and ureas employing a Grignard base, an amine and an ester

Methods for the synthesis of amides are extremely important given huge prevalence of this functional group in biological systems, as well as in the pharmaceutical industry. The ACS Green Chemistry Institute Pharmaceutical Roundtable have identified the amide bond formation as one of the most importa...

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Bibliographic Details
Main Authors: Omolola Gbadebo, Karen Fox, Grace Sutton, Paul V. Murphy, Dennis Smith, Patrick O'Leary
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Results in Chemistry
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211715621001582