Potassium channel TASK-5 forms functional heterodimers with TASK-1 and TASK-3 to break its silence

Abstract TASK-5 (KCNK15) belongs to the acid-sensitive subfamily of two-pore domain potassium (K2P) channels, which includes TASK-1 and TASK-3. TASK-5 stands out as K2P channel for which there is no functional data available, since it was reported in 2001 as non-functional and thus “silent”. Here we...

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Detalhes bibliográficos
Main Authors: Susanne Rinné, Florian Schick, Kirsty Vowinkel, Sven Schütte, Cornelius Krasel, Silke Kauferstein, Martin K.-H. Schäfer, Aytug K. Kiper, Thomas Müller, Niels Decher
Formato: Artigo
Idioma:English
Publicado em: Nature Portfolio 2024-08-01
Colecção:Nature Communications
Acesso em linha:https://doi.org/10.1038/s41467-024-51288-8