STAT1 Signaling in Astrocytes Is Essential for Control of Infection in the Central Nervous System

STAT1 Signaling in Astrocytes Is Essential for Control of Infection in the Central Nervous System

ABSTRACT The local production of gamma interferon (IFN-γ) is important to control Toxoplasma gondii in the brain, but the basis for these protective effects is not fully understood. The studies presented here reveal that the ability of IFN-γ to inhibit parasite replication in astrocytes in vitro is...

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Bibliographic Details
Main Authors: Shinya Hidano, Louise M. Randall, Lucas Dawson, Hans K. Dietrich, Christoph Konradt, Peter J. Klover, Beena John, Tajie H. Harris, Qun Fang, Bradley Turek, Takashi Kobayashi, Lothar Hennighausen, Daniel P. Beiting, Anita A. Koshy, Christopher A. Hunter
Format: Article
Language:English
Published: American Society for Microbiology 2016-12-01
Series:mBio
Online Access:https://journals.asm.org/doi/10.1128/mBio.01881-16

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https://journals.asm.org/doi/10.1128/mBio.01881-16

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