A combinatorial approach to uncover an additional Integrator subunit

Summary: RNA polymerase II (RNAPII) controls expression of all protein-coding genes and most noncoding loci in higher eukaryotes. Calibrating RNAPII activity requires an assortment of polymerase-associated factors that are recruited at sites of active transcription. The Integrator complex is one of...

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Bibliographic Details
Main Authors: Sarah R. Offley, Moritz M. Pfleiderer, Avery Zucco, Angelique Fraudeau, Sarah A. Welsh, Michal Razew, Wojciech P. Galej, Alessandro Gardini
Format: Article
Language:English
Published: Elsevier 2023-03-01
Series:Cell Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124723002553