MERTK interactions with SH2-domain proteins in the retinal pigment epithelium.

MERTK interactions with SH2-domain proteins in the retinal pigment epithelium.

The receptor tyrosine kinase MERTK plays an essential role in the phagocytic uptake of shed photoreceptor membranes by the retinal pigment epithelium (RPE). A fundamental aspect of signal transduction by receptor tyrosine kinases involves autophosphorylation of tyrosine residues that recruit Src-hom...

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Bibliographic Details
Main Authors: Shameka J Shelby, Karen Colwill, Sirano Dhe-Paganon, Tony Pawson, Debra A Thompson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3563642?pdf=render

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http://europepmc.org/articles/PMC3563642?pdf=render

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