TP53 in Biology and Treatment of Osteosarcoma

TP53 in Biology and Treatment of Osteosarcoma

The <i>TP53</i> gene is mutated in 50% of human tumors. Oncogenic functions of mutant <i>TP53</i> maintain tumor cell proliferation and tumor growth also in osteosarcomas. We collected data on <i>TP53</i> mutations in patients to indicate which are more common and...

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Bibliographic Details
Main Authors: Kamil Jozef Synoradzki, Ewa Bartnik, Anna M. Czarnecka, Michał Fiedorowicz, Wiktoria Firlej, Anna Brodziak, Agnieszka Stasinska, Piotr Rutkowski, Paweł Grieb
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Cancers
Subjects:
TP53
osteosarcoma
gene therapy
animal models
pharmacological modulation
Online Access:https://www.mdpi.com/2072-6694/13/17/4284

Internet

https://www.mdpi.com/2072-6694/13/17/4284

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