Process- and product-related impurities in the ChAdOx1 nCov-19 vaccine

Process- and product-related impurities in the ChAdOx1 nCov-19 vaccine

ChAdOx1 nCov-19 and Ad26.COV2.S are approved vaccines inducing protective immunity against SARS-CoV-2 infection in humans by expressing the Spike protein of SARS-CoV-2. We analyzed protein content and protein composition of ChAdOx1 nCov-19 and Ad26.COV2.S by biochemical methods and by mass spectrome...

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Bibliographic Details
Main Authors: Lea Krutzke, Reinhild Rösler, Ellen Allmendinger, Tatjana Engler, Sebastian Wiese, Stefan Kochanek
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2022-07-01
Series:eLife
Subjects:
adenovirus
vaccine
SARS-CoV-2
process-related impurities
host cell proteins
Online Access:https://elifesciences.org/articles/78513

Internet

https://elifesciences.org/articles/78513

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