EphA2 Is a Therapy Target in EphA2-Positive Leukemias but Is Not Essential for Normal Hematopoiesis or Leukemia.

Members of the Eph family of receptor tyrosine kinases and their membrane bound ephrin ligands have been shown to play critical roles in many developmental processes and more recently have been implicated in both normal and pathological processes in post-embryonic tissues. In particular, expression...

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Bibliographic Details
Main Authors: Sara Charmsaz, Kirrilee Beckett, Fiona M Smith, Claudia Bruedigam, Andrew S Moore, Fares Al-Ejeh, Steven W Lane, Andrew W Boyd
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4470658?pdf=render