Microsatellite instability in prostate cancer by PCR or next-generation sequencing

Microsatellite instability in prostate cancer by PCR or next-generation sequencing

Abstract Background Microsatellite instability (MSI) is now being used as a sole biomarker to guide immunotherapy treatment for men with advanced prostate cancer. Yet current molecular diagnostic tests for MSI have not been evaluated for use in prostate cancer. Methods We evaluated two next-generati...

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Bibliographic Details
Main Authors: Jennifer A. Hempelmann, Christina M. Lockwood, Eric Q. Konnick, Michael T. Schweizer, Emmanuel S. Antonarakis, Tamara L. Lotan, Bruce Montgomery, Peter S. Nelson, Nola Klemfuss, Stephen J. Salipante, Colin C. Pritchard
Format: Article
Language:English
Published: BMJ Publishing Group 2018-04-01
Series:Journal for ImmunoTherapy of Cancer
Subjects:
Prostate adenocarcinoma
Microsatellite instability
MSI
Promega
Capillary electrophoresis
Mismatch repair
Online Access:http://link.springer.com/article/10.1186/s40425-018-0341-y

Internet

http://link.springer.com/article/10.1186/s40425-018-0341-y

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