Flavone-based dual PARP-Tubulin inhibitor manifesting efficacy against endometrial cancer

Flavone-based dual PARP-Tubulin inhibitor manifesting efficacy against endometrial cancer

AbstractStructural tailoring of the flavone framework (position 7) via organopalladium-catalyzed C–C bond formation was attempted in this study. The impact of substituents with varied electronic effects (phenyl ring, position 2 of the benzopyran scaffold) on the antitumor properties was also assesse...

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Bibliographic Details
Main Authors: Sachin Sharma, Kavya Chandra, Aliva Naik, Anamika Sharma, Ram Sharma, Amandeep Thakur, Ajmer Singh Grewal, Ashwani K. Dhingra, Arnab Banerjee, Jing Ping Liou, Santosh Kumar Guru, Kunal Nepali
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Journal of Enzyme Inhibition and Medicinal Chemistry
Subjects:
Flavone
benzopyran
PARP
tubulin
inhibitor
endometrial cancer
Online Access:https://www.tandfonline.com/doi/10.1080/14756366.2023.2276665

Internet

https://www.tandfonline.com/doi/10.1080/14756366.2023.2276665

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