Cryptococcal proteases exhibit the potential to activate the latent SARS-CoV-2 spike protein

Cryptococcal proteases exhibit the potential to activate the latent SARS-CoV-2 spike protein

Background: The COVID-19 pandemic has affected more than 650 million people and resulted in over 6.8 million deaths. Notably, the disease could co-manifest with microbial infections, like cryptococcosis, which also presents as a primary lung infection. Objective: In this contribution, we sought to d...

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Bibliographic Details
Main Authors: Nozethu Mjokane, Saheed Sabiu, Olufemi S. Folorunso, Onele M.N. Gcilitshana, Jacobus Albertyn, Carolina H. Pohl, Olihile M. Sebolai
Format: Article
Language:English
Published: Elsevier 2024-02-01
Series:Journal of Infection and Public Health
Subjects:
Cryptococcal protease
Furin protease
HEK-293 T cells
Protein-protein docking
SARS-CoV-2 spike protein
Online Access:http://www.sciencedirect.com/science/article/pii/S1876034123004446

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http://www.sciencedirect.com/science/article/pii/S1876034123004446

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