ALG-2 attenuates COPII budding in vitro and stabilizes the Sec23/Sec31A complex.

Coated vesicles mediate the traffic of secretory and membrane cargo proteins from the endoplasmic reticulum (ER) to the Golgi apparatus. The coat protein complex (COPII) involved in vesicle budding is constituted by a GTPase, Sar1, the inner coat components of Sec23/Sec24 and the components of the o...

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Bibliographic Details
Main Authors: Jonas M la Cour, Adam J Schindler, Martin W Berchtold, Randy Schekman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3777911?pdf=render