Malaria Induces Anemia through CD8<sup>+</sup> T Cell-Dependent Parasite Clearance and Erythrocyte Removal in the Spleen

Malaria Induces Anemia through CD8<sup>+</sup> T Cell-Dependent Parasite Clearance and Erythrocyte Removal in the Spleen

ABSTRACT  Severe malarial anemia (SMA) in semi-immune individuals eliminates both infected and uninfected erythrocytes and is a frequent fatal complication. It is proportional not to circulating parasitemia but total parasite mass (sequestered) in the organs. Thus, immune responses that clear parasi...

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Những tác giả chính: Innocent Safeukui, Noé D. Gomez, Aanuoluwa A. Adelani, Florence Burte, Nathaniel K. Afolabi, Rama Akondy, Peter Velazquez, Anthony Holder, Rita Tewari, Pierre Buffet, Biobele J. Brown, Wuraola A. Shokunbi, David Olaleye, Olugbemiro Sodeinde, James Kazura, Rafi Ahmed, Narla Mohandas, Delmiro Fernandez-Reyes, Kasturi Haldar
Định dạng: Bài viết
Ngôn ngữ:English
Được phát hành: American Society for Microbiology 2015-02-01
Loạt:mBio
Truy cập trực tuyến:https://journals.asm.org/doi/10.1128/mBio.02493-14

Internet

https://journals.asm.org/doi/10.1128/mBio.02493-14

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