Uridylation and PABP Cooperate to Repair mRNA Deadenylated Ends in Arabidopsis

Uridylation emerges as a key modification promoting mRNA degradation in eukaryotes. In addition, uridylation by URT1 prevents the accumulation of excessively deadenylated mRNAs in Arabidopsis. Here, we show that the extent of mRNA deadenylation is controlled by URT1. By using TAIL-seq analysis, we d...

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Bibliographic Details
Main Authors: Hélène Zuber, Hélène Scheer, Emilie Ferrier, François Michaël Sement, Pierre Mercier, Benjamin Stupfler, Dominique Gagliardi
Format: Article
Language:English
Published: Elsevier 2016-03-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124716301814