RUNX1 targeting AKT3 promotes alveolar hypercoagulation and fibrinolytic inhibition in LPS induced ARDS

RUNX1 targeting AKT3 promotes alveolar hypercoagulation and fibrinolytic inhibition in LPS induced ARDS

Abstract Background Alveolar hypercoagulation and fibrinolytic inhibition are mainly responsible for massive alveolar fibrin deposition, which are closely related with refractory hypoxemia in acute respiratory distress syndrome (ARDS). Our previous study testified runt-related transcription factor (...

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Bibliographic Details
Main Authors: Chuan Xiao, Jiaoyangzi Liu, Yumei Cheng, Yingxia Wu, Qing Li, Xianjun Chen, Jia Yuan, Qi Dong, Lu Li, Ying liu, Feng Shen
Format: Article
Language:English
Published: BMC 2024-01-01
Series:Respiratory Research
Subjects:
AKT3
Runt-related transcription factor 1
Alveolar hypercoagulation
Fibrinolytic inhibition
Acute respiratory distress syndrome
Online Access:https://doi.org/10.1186/s12931-024-02689-2

Internet

https://doi.org/10.1186/s12931-024-02689-2

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