Primary phagocytosis of neurons by inflamed microglia: potential roles in neurodegeneration

Microglial phagocytosis of dead or dying neurons can be beneficial by preventing secondary necrosis and release of pro-inflammatory intracellular components. However, there is now evidence that under certain conditions microglia can also phagocytose viable neurons, thus executing their death. In par...

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Váldodahkkit: Jonas J Neher, Urte eNeniskyte, Guy C Brown
Materiálatiipa: Artihkal
Giella:English
Almmustuhtton: Frontiers Media S.A. 2012-02-01
Ráidu:Frontiers in Pharmacology
Fáttát:
Liŋkkat:http://journal.frontiersin.org/Journal/10.3389/fphar.2012.00027/full