WDR76 regulates 5-fluorouracil sensitivity in colon cancer via HRAS

Abstract Background WD repeat domain 76 (WDR76) has been reported in multiple tumors, while without relation to chemotherapy resistance. 5-fluorouracil (5-FU) is widely adopted in treating colon cancer. However, the resistance of WDR76 and 5-FU in colon cancer remains unclear. Methods Limma package...

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Bibliographic Details
Main Authors: Yunlong Hu, Xiao Tan, Lin Zhang, Xiang Zhu, Xiangyao Wang
Format: Article
Language:English
Published: Springer 2023-04-01
Series:Discover Oncology
Subjects:
Online Access:https://doi.org/10.1007/s12672-023-00656-9