Polymeric Delivery Systems as a Potential Vaccine against Visceral Leishmaniasis: Formulation Development and Immunogenicity

Polymeric Delivery Systems as a Potential Vaccine against Visceral Leishmaniasis: Formulation Development and Immunogenicity

Recent studies suggest that the association of antigens in microparticles increases the anti-<i>Leishmania</i> vaccine immunogenicity. This study aims to investigate the in situ effect of the adjuvant performance consisting of chitosan-coated poly(<i>D</i>,<i>L</i>...

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Bibliographic Details
Main Authors: João Guilherme Lino da Silva, Ana Alice Maia Gonçalves, Liliam Teixeira Oliveira, Giani Martins Garcia, Maurício Azevedo Batista, Ludmila Zanandreis de Mendonça, Kelvinson Fernandes Viana, Rita de Cássia Oliveira Sant’Ana, Otoni Alves de Oliveira Melo Júnior, Denise Silveira-Lemos, Walderez Ornelas Dutra, Olindo Assis Martins-Filho, Alexsandro Sobreira Galdino, Sandra Aparecida Lima de Moura, Vanessa Carla Furtado Mosqueira, Rodolfo Cordeiro Giunchetti
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Vaccines
Subjects:
visceral leishmaniasis
submicrometric particles
vaccine
polymeric nanoparticles
Online Access:https://www.mdpi.com/2076-393X/11/8/1309

Internet

https://www.mdpi.com/2076-393X/11/8/1309

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