Within the Ischemic Penumbra, Sub-Cellular Compartmentalization of Heat Shock Protein 70 Overlaps with Autophagy Proteins and Fails to Merge with Lysosomes

Within the Ischemic Penumbra, Sub-Cellular Compartmentalization of Heat Shock Protein 70 Overlaps with Autophagy Proteins and Fails to Merge with Lysosomes

The brain area which surrounds the frankly ischemic region is named the <i>area penumbra</i>. In this area, most cells are spared although their oxidative metabolism is impaired. <i>area penumbra</i> is routinely detected by immunostaining of a molecule named Heat Shock Prote...

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Bibliographic Details
Main Authors: Federica Mastroiacovo, Francesca Biagioni, Paola Lenzi, Gloria Lazzeri, Michela Ferrucci, Stefano Puglisi-Allegra, Alessandro Frati, Ferdinando Nicoletti, Francesco Fornai
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Molecules
Subjects:
autophagy vacuoles
lysosomes
cell clearing systems
ultrastructural stoichiometry
Online Access:https://www.mdpi.com/1420-3049/27/10/3122

Internet

https://www.mdpi.com/1420-3049/27/10/3122

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