CD138 Is Expressed in Different Entities of Salivary Gland Cancer and Their Lymph Node Metastases and Therefore Represents a Potential Therapeutic Target

CD138 Is Expressed in Different Entities of Salivary Gland Cancer and Their Lymph Node Metastases and Therefore Represents a Potential Therapeutic Target

Advanced salivary gland carcinomas (SGC) often lack therapeutic options. Agents targeting CD138 have recently shown promising results in clinical trials for multiple myeloma and a preclinical trial for triple-negative breast cancer. Immunohistochemistry for CD138 was performed for all patients who h...

Full description

Bibliographic Details
Main Authors: Marcel Mayer, Lisa Nachtsheim, Franziska Hoffmann, Ferdinand von Eggeling, Orlando Guntinas-Lichius, Johanna Prinz, Jens Peter Klußmann, Alexander Quaas, Christoph Arolt, Philipp Wolber
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:International Journal of Molecular Sciences
Subjects:
salivary gland neoplasm
immunohistochemistry
head and neck cancer
targeted therapy
CD138
Syndecan-1
Online Access:https://www.mdpi.com/1422-0067/23/16/9037

Internet

https://www.mdpi.com/1422-0067/23/16/9037

Similar Items