Effect of prebiotic oligosaccharides on bowel habit and the gut microbiota in children with functional constipation (Inside study): study protocol for a randomised, placebo-controlled, multi-centre trial

Effect of prebiotic oligosaccharides on bowel habit and the gut microbiota in children with functional constipation (Inside study): study protocol for a randomised, placebo-controlled, multi-centre trial

Abstract Background Functional constipation (FC) in children is a common gastrointestinal disorder with a worldwide-pooled prevalence of 9.5%. Complaints include infrequent bowel movements, painful defecation due to hard and/or large stools, faecal incontinence, and abdominal pain. Prebiotic oligosa...

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Bibliographic Details
Main Authors: Carrie A. M. Wegh, Margriet H. C. Schoterman, Elaine E. Vaughan, Sofie C. C. van der Zalm, Hauke Smidt, Clara Belzer, Marc A. Benninga
Format: Article
Language:English
Published: BMC 2024-04-01
Series:Trials
Subjects:
Gastroenterology
Nutrition
Gut microbiota
Paediatrics
Oligosaccharides
Prebiotic
Online Access:https://doi.org/10.1186/s13063-024-08050-8

Internet

https://doi.org/10.1186/s13063-024-08050-8

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