Efficacy and safety of inhaled carbon monoxide during pulmonary inflammation in mice.

Pulmonary inflammation is a major contributor to morbidity in a variety of respiratory disorders, but treatment options are limited. Here we investigate the efficacy, safety and mechanism of action of low dose inhaled carbon monoxide (CO) using a mouse model of lipopolysaccharide (LPS)-induced pulmo...

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Bibliographic Details
Main Authors: Michael R Wilson, Kieran P O'Dea, Anthony D Dorr, Hirotoshi Yamamoto, Michael E Goddard, Masao Takata
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-07-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2903490?pdf=render