Helicobacter pylori Type IV Secretion System and Its Adhesin Subunit, CagL, Mediate Potent Inflammatory Responses in Primary Human Endothelial Cells

Helicobacter pylori Type IV Secretion System and Its Adhesin Subunit, CagL, Mediate Potent Inflammatory Responses in Primary Human Endothelial Cells

The Gram-negative bacterium, Helicobacter pylori, causes chronic gastritis, peptic ulcers, and gastric cancer in humans. Although the gastric epithelium is the primary site of H. pylori colonization, H. pylori can gain access to deeper tissues. Concurring with this notion, H. pylori has been found i...

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Bibliographic Details
Main Authors: Mona Tafreshi, Jyeswei Guan, Rebecca J. Gorrell, Nicole Chew, Yue Xin, Virginie Deswaerte, Manfred Rohde, Roger J. Daly, Richard M. Peek, Brendan J. Jenkins, Elizabeth M. Davies, Terry Kwok
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-02-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Helicobacter
type IV secretion
interleukin-8
endothelial cells
inflammation
CagL
Online Access:http://journal.frontiersin.org/article/10.3389/fcimb.2018.00022/full

Internet

http://journal.frontiersin.org/article/10.3389/fcimb.2018.00022/full

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