Development of a rat capnoperitoneum phantom to study drug aerosol deposition in the context of anticancer research on peritoneal carcinomatosis

Development of a rat capnoperitoneum phantom to study drug aerosol deposition in the context of anticancer research on peritoneal carcinomatosis

Abstract Pressurized Intraperitoneal Aerosol Chemotherapy (PIPAC) is a promising approach with a high optimization potential for the treatment of peritoneal carcinomatosis. To study the efficacy of PIPAC and drugs, first rodent cancer models were developed. But inefficient drug aerosol supply and kn...

Full description

Bibliographic Details
Main Authors: Daniel Göhler, Antje Geldner, Ralf Gritzki, Franz Lohse, Stephan Große, Julien Sobilo, Clemens Felsmann, Jonathan R. Buggisch, Alain Le Pape, Andreas Rudolph, Michael Stintz, Urs Giger-Pabst
Format: Article
Language:English
Published: Nature Portfolio 2021-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-01332-0

Internet

https://doi.org/10.1038/s41598-021-01332-0

Similar Items