Interaction of Tau with the chemokine receptor, CX3CR1 and its effect on microglial activation, migration and proliferation

Interaction of Tau with the chemokine receptor, CX3CR1 and its effect on microglial activation, migration and proliferation

Abstract Alzheimer’s disease (AD) is a neurodegenerative disease that leads to progressive loss of memory and dementia. The pathological hallmarks of AD include extracellular accumulation of amyloid-β peptides forming senile plaques and intracellular accumulation of Tau oligomers and filamentous spe...

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Bibliographic Details
Main Authors: Hariharakrishnan Chidambaram, Rashmi Das, Subashchandrabose Chinnathambi
Format: Article
Language:English
Published: BMC 2020-09-01
Series:Cell & Bioscience
Subjects:
Alzheimer’s disease
Microglia
Neuron
Tau
Fractalkine
CX3CR1 receptor
Online Access:http://link.springer.com/article/10.1186/s13578-020-00474-4

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http://link.springer.com/article/10.1186/s13578-020-00474-4

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