Knockdown of lncRNA MALAT1 attenuates renal interstitial fibrosis through miR-124-3p/ITGB1 axis

Abstract Renal interstitial fibrosis (RIF) considered the primary irreversible cause of chronic kidney disease. Recently, accumulating studies demonstrated that lncRNAs play an important role in the pathogenesis of RIF. However, the underlying exact mechanism of lncRNA MALAT1 in RIF remains barely k...

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Bibliographic Details
Main Authors: Weiping Xia, Xiang Chen, Zewu Zhu, Hequn Chen, Bingsheng Li, Kangning Wang, Li Huang, Zhi Liu, Zhi Chen
Format: Article
Language:English
Published: Nature Portfolio 2023-10-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-45188-y