Cisplatin Resistance in Epstein–Barr-Virus-Associated Gastric Carcinoma Acquired through <i>ATM</i> Methylation

Cisplatin Resistance in Epstein–Barr-Virus-Associated Gastric Carcinoma Acquired through <i>ATM</i> Methylation

Epstein–Barr-virus-associated gastric carcinoma (EBVaGC), first reported in 1992, currently accounts for 10% of all gastric carcinoma worldwide. EBVaGC has unique DNA hypermethylation phenotypes that allow for higher proportions of DNA methylation than any other gastric cancer. CpG islands in the ge...

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Bibliographic Details
Main Authors: Sun Hee Lee, Su Jin Choi, Wonhyeok Choi, Subin Cho, Miyeon Cho, Dong Sun Kim, Byung Woog Kang, Jong Gwang Kim, You Mie Lee, Hyosun Cho, Hyojeung Kang
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Cancers
Subjects:
cisplatin
5-Azacytidine
DNA methylation
Epstein–Barr virus
DNMT3A
ATM
Online Access:https://www.mdpi.com/2072-6694/13/17/4252

Internet

https://www.mdpi.com/2072-6694/13/17/4252

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